Those brown spots occur when the brown pigment lipofuscin accumulates in the upper layers of the Skin Whitening. Free radicals are aggressive oxygen molecules that are formed by UV irradiation, they trigger a protective mechanism in the skin. When our skin, but long years of intense UV radiation exposure, but does not only attack by free radicals at the same time will slow down the production of endogenous antioxidants. Local pigmentary changes may be the result: The skin is more pigments, and it forms small, dark spots – the so-called “age spots.